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接种疫苗和未接种疫苗的COVID-2019住院患者中死亡和疾病严重性的风险因素:一项回顾性队列研究

Guilherme Jorge Costa1, José Roberto da Silva Junior2, Caio Cesar Arruda da Silva2

  • 1. Departamento de Ensino e Pesquisa, Hospital Alfa, Recife (PE) Brasil.

Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia
|September 20, 2023
PubMed
概括

接种COVID-19疫苗显著减少严重疾病和死亡. 增剂剂量提供累积保护,三剂量提供了最实质性的对住院患者的死亡率的好处.

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The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
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Protein-drug binding, a pivotal aspect of pharmacokinetics, is subject to considerable variability influenced by an array of patient-related factors. The intricate interplay of age, individual differences, and pathological conditions significantly impact the binding dynamics and subsequent pharmacological effects.
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