2008年至2017年哥伦比亚马尼萨莱斯的结肠直肠癌生存率:基于人口的研究
Eduardo Antonio Guzmán-Gallego1, Nelson Enrique Arias-Ortiz2, Juan David Rodríguez-Betancourt2
1Universidad de Caldas, Health Research Institute, Basic Clinical Department - Manizales, Colombia.
Revista brasileira de epidemiologia = Brazilian journal of epidemiology
|September 20, 2023
概括
大肠直肠癌 (CRC) 的存活率在马尼扎尔人中很低,五年存活率为45.8%. 老年,晚年阶段和中等社会经济地位显著降低了CRC患者的存活率.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 结肠直肠癌 (CRC) 仍然是一个重大的全球健康挑战.
- 了解生存率和相关因素对于改善患者的治疗结果至关重要.
研究的目的:
- 为了确定马尼萨莱斯的结直肠癌 (CRC) 患者的5年生存率.
- 为了确定影响CRC存活的患者和瘤特征.
主要方法:
- 一项纵向研究分析了2008-2017年间发生的侵入性CRC病例 (n=850).
- 使用Cox多变量回归计算和分析了因果特异性和净存活率.
- 随访延长至2021年8月24日.
主要成果:
- 对CRC的5年特异性存活率为45.8%.
- 75岁以上的患者 (HR=1.83) 和在晚期诊断的患者 (III期HR=2.5,IV期HR=5.7) 的生存率明显较低.
- 中等社会经济地位与较低的生存率相关 (HR=1.52),而不是较低的社会经济地位或医疗保险制度.
结论:
- 马尼萨莱斯大约50%的结直肠癌患者的存活时间不会超过5年.
- 影响生存的关键因素包括晚年,诊断时的晚期临床阶段和中等社会经济地位.
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