塞尔吉佩肺结核病例和治疗结果的时间序列,2012-2021年
Jefferson Felipe Calazans Batista1, Vitória Steffany de Oliveira Santos1, Carla Viviane Freitas de Jesus1
1Universidade Tiradentes - Aracaju (SE), Brazil.
Revista brasileira de epidemiologia = Brazilian journal of epidemiology
|September 20, 2023
概括
塞尔吉佩的结核病发病率增加,而治疗中断和死亡率下降. 没有观察到季节性,但快速分子测试 (MTB-RIF) 与发病率上升相关.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 传染性疾病 传染性疾病
背景情况:
- 结核病 (TB) 仍然是一个重大的全球卫生挑战.
- 了解时间趋势和治疗结果对于有效的控制策略至关重要.
- 引入MTB-RIF测试等快速诊断工具可能会影响结核病流行病学.
研究的目的:
- 分析塞尔吉佩的结核病发病率和治疗结果的时间趋势.
- 调查该地区结核病的潜在季节性.
- 评估MTB-RIF测试对TB时间序列和结果的影响.
- 评估结核病治疗结果,包括治愈,中断和死亡率.
主要方法:
- 使用Datasus数据对结核病例和结局 (治愈,中断,死亡) 的生态研究.
- 计算发病率,死亡率和治愈/中断比例.
- 使用普莱斯-温斯顿回归 (2021年1月至12月) 的时间序列分析.
主要成果:
- 结核病发病率为36.35/100,000,每月增加0.44%.
- 治愈率为64.0% (稳定趋势);治疗中断率为13.3% (下降-0.73%/月).
- 死亡率为1.92/100,000 (停滞不前的趋势). 实施MTB-RIF与每月发病率增加0.65%相关. 没有检测到季节性.
结论:
- 塞尔吉佩的结核病发病率上升,治疗中断减少,死亡率降低.
- 没有确定结核病的季节性模式.
- MTB-RIF测试似乎对结核病发病率产生增长效应.
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