在菌感染中抗真菌治疗的持续时间:什么时候足够?
Vera Portillo1, Dionysios Neofytos
1Division of Infectious Diseases, University Hospital of Geneva, Geneva, Switzerland.
Current opinion in infectious diseases
|September 20, 2023
概括
确定侵入性菌感染 (IMI) 抗真菌治疗的最佳持续时间是具有挑战性的,因为解决标准不太清楚. 需要证据来指导在免疫受损患者中停止治疗的决定.
科学领域:
- 菌类学 菌类学是指菌类学.
- 传染性疾病 传染性疾病
- 临床医学 临床医学
背景情况:
- 侵入性菌感染 (IMI) 是免疫功能低下个体的严重并发症.
- 目前的指导方针缺乏停止治疗的准确定义,依赖于临床/放射学解决和免疫恢复.
- 现有的数据表明治疗持续时间较长,往往会模糊二次预防的线.
结论:
- 停止IMI抗真菌治疗的决定是基于有限的证据和专家意见.
- 为了确定最佳的治疗持续时间,需要进行更多的研究.
- 开发实用的算法对于指导临床医生IMI管理至关重要.
更多相关视频
07:19A 96 Well Microtiter Plate-based Method for Monitoring Formation and Antifungal Susceptibility Testing of Candida albicans Biofilms
Published on: October 21, 2010
45.1K
06:49Reduced Itraconazole Concentration and Durations Are Successful in Treating Batrachochytrium dendrobatidis Infection in Amphibians
Published on: March 14, 2014
11.6K
相关概念视频
Fungal Group Zygomycota
41
Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
41
Fungal Phylum Microsporidia
41
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
41
Antimicrobial Effectiveness
43
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
43
Pulmonary Tuberculosis V
200
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
200
