左心室上至基底压力比率与大动脉置换后的导电障碍之间的关联
Dorien Laenens1, Jan Stassen2, Xavier Galloo3
1Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
概括
异常的顶端至底部应变比,表明间歇性纤维化,与大动脉置换 (AVR) 后的导电障碍有关. 这一发现有助于识别AVR后需要起器的患者.
科学领域:
- 心脏病学 心脏病学
- 心脏成像 - - 心脏成像
- 电子生理学 电子生理学
背景情况:
- 严重的大动脉狭窄需要大动脉置换 (AVR).
- 导电障碍,如捆绑分支阻塞,可以发生在AVR后.
- 左心室垂至基底的纵向应变差异可能表明基底间歇性纤维化.
研究的目的:
- 为了确定左心室顶至基底的纵向应变差异是否与AVR后的导电障碍有关.
- 为了研究这种应变比对心脏起器植入的预测价值.
主要方法:
- 包括接受AVR的严重大动脉狭窄患者.
- 计算了顶点和基点应变比率;值>1.9被认为是异常的.
- 在2年内对完整捆绑分支块或永久心脏起器植入进行后续评估.
主要成果:
- 包括274名患者;27%的人患有导电障碍或接受了起器.
- 在患有导电障碍的患者中,异常的顶点-基点应变比较频繁.
- 异常应变比是AVR后传导障碍的独立预测因素,包括经过透导管AVR后.
结论:
- 在AVR之后,顶点至基点应变比独立地与导电障碍有关.
- 这一比率可以帮助在AVR后的患者中对心脏起器植入的风险分层.
相关概念视频
Aortic Regurgitation III: Medical Management
24
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
24
Mitral Stenosis I: Introduction
15
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
15
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
23
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
23
Aortic Regurgitation I: Introduction
10
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
10
Mitral Regurgitation I: Introduction
15
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
15
Mitral Stenosis II: Clinical features and Diagnostic Tests
22
Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
22


