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基于共进化的计算方法来检测表皮生长因子受体的抵抗机制

Gyan Prakash Rai1, Asheesh Shanker1

  • 1Department of Bioinformatics, Central University of South Bihar, Gaya, Bihar 824236, India.

Biochimica et biophysica acta. Molecular cell research
|September 20, 2023
PubMed
概括

表皮生长因子受体 (EGFR) 的补偿突变驱动对非小细胞肺癌治疗方法的耐药性. 这些EGFR突变改变了药物结合口袋,影响了氨酸激酶抑制剂的有效性.

关键词:
共同进化的共同进化药物耐药性 药物耐药性 药物耐药性欧洲农业基金会 (EGFR) 是一个基金.埃尔洛丁尼布 (Erlotinib) 是一种药物.盖菲提尼布 (Gefitinib) 是一种药物.肺癌是一种肺癌.突变 突变 突变 突变 突变

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