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Updated: Jul 16, 2025

Macrophage Cholesterol Depletion and Its Effect on the Phagocytosis of Cryptococcus neoformans
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Published on: December 19, 2014

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AMPK激活剂通过抑制mTOR通路来抑制巨细胞中的胆固醇积累

Reina Owaki1, Hiromasa Aoki1, Kohki Toriuchi1

  • 1Department of Pathobiology, Nagoya City University Graduate School of Pharmaceutical Sciences, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi, 467-8603, Japan.

Experimental cell research
|September 20, 2023
PubMed
概括

AMP激活蛋白激酶 (AMPK) 激活通过抑制巨细胞中的mTOR来抑制动脉样硬化,促进胆固醇排泄并减少泡细胞的形成. 这表明心血管疾病预防和治疗的新治疗点.

关键词:
这就是AMPKK.动脉样硬化是一种动脉样硬化.胆固醇的排放流出.巨细胞是一个巨细胞.在mTOROR中使用mTOR.

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