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Updated: Jul 16, 2025

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CFTR折叠:从结构和蛋白质稳定到囊性纤维化个性化医学

Eli Fritz McDonald1,2, Jens Meiler1,2,3,4, Lars Plate1,5,6

  • 1Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.

ACS chemical biology
|September 20, 2023
PubMed
概括

囊性纤维化 (CF) 治疗正在改善,这要归功于稳定囊性纤维化跨膜导电性调节器 (CFTR) 蛋白质的校正剂. 了解CFTR折叠和突变特异性药物反应是个性化CF医学的关键.

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