结合深度学习和放射学,实现自动化,客观,全面的骨矿物质密度评估,使用低剂量胸部计算机断层扫描
Shigeng Wang1, Xiaoyu Tong1, Yong Fan1
1Department of Radiology, First Affiliated Hospital of Dalian Medical University, Shahekou District, Lianhe Road, Dalian, Liaoning, China (S.W., X.T., Y.F., M.H., Y.L., X.F.).
Academic radiology
|September 20, 2023
概括
一个自动化的深度学习模型使用低剂量胸部CT扫描精确地选骨质疏松症. 这种方法使得机会性骨密度评估,改善早期检测和骨质损失的管理.
科学领域:
- 医疗成像医学成像
- 人工智能在医学中的应用
- 放射学 放射学是一门学科.
背景情况:
- 骨质疏松症查通常需要专门的骨密度测试.
- 低剂量胸部计算机断层扫描 (LDCT) 是广泛可用的,并可能被用于机会性查.
研究的目的:
- 开发一个智能诊断模型用于骨质疏松症查使用LDCT.
- 整合自动深度学习用于胸椎断骨 (TVCB) 分段和放射学分析.
主要方法:
- 一个深度学习模型 (VB-Net) 被训练为自动TVCB细分.
- 在细分的TVCB上进行了放射学分析,以预测骨矿物质密度 (BMD).
- 在442名参与者身上训练和验证了模型,将自动细分 (ASeg) 与手动细分 (MSeg) 进行比较.
主要成果:
- 该TVCB自动细分模型实现了高精度 (迪斯系数为0.988和0.939).
- 该ASeg模型的诊断性能 (AUC) 与MSeg模型的诊断性能 (AUC) 在识别正常/异常的骨质疏松症和骨质疏松症/骨质疏松症方面相似.
- 对于ASeg模型的AUC值很高,例如,在第一级模型的外部测试队列中为0.965.
结论:
- 完全自动化的 TVCB 分段和 BMD 评估管道是可行的.
- 这种方法可以利用现有的胸部LDCT扫描进行机会性BMD查.
- 开发的模型显示了广泛的骨质疏松症查的潜力.
更多相关视频
相关概念视频
Radiological Investigation I: X-ray and CT
278
Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
278
X-ray Imaging
5.6K
German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
5.6K
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
39
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
39
Imaging Studies I: CT and MRI
275
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
275


