对前性研究进行系统审查,评估风险因素以预测精神性厌食症发病的风险因素
Jean-Philippe Charrat1,2, Catherine Massoubre3,4,5, Natacha Germain3,4,5
1TAPE (Eating Disorders, Addictions and Extreme Bodyweight) Laboratory, University Jean Monnet, Saint Etienne, France. jean.philippe.charrat@univ-st-etienne.fr.
Journal of eating disorders
|September 20, 2023
概括
预测神经性厌食症 (AN) 发病仍然具有挑战性,因为前性数据不足. 目前的研究表明,风险因素之间可能存在双向影响,但对于青少年早期干预还没有确定的预测标志物.
科学领域:
- 饮食障碍 研究 研究 研究
- 儿童和青少年精神病学
- 公共卫生 公共卫生
背景情况:
- 神经性厌食症 (AN) 的出现与病例控制研究中确定的多种因素有关.
- 现有的研究主要依赖于回顾性分析,限制了预测准确性.
- 未来研究对于了解AN的发展轨迹至关重要.
研究的目的:
- 系统地审查前性研究,评估对神经性厌食症 (AN) 发病的预测.
- 为早期干预策略确定可靠的预测标记.
- 评估AN预测现有前性研究的方法质量.
主要方法:
- 在PubMed,PsycINFO和Cochrane数据库中的系统文献搜索.
- 遵守ARMSTAR 2和PRISMA 2020研究选择和报告指南.
- 使用唐斯和黑名单的方法质量评估.
主要成果:
- 三项针对普通人群的前性研究符合纳入标准;其方法质量不足于最佳.
- 在低体重和身体不满等风险因素之间注意到了双向放大效应.
- 讨论了11项额外的纵向研究,以追溯的AN发病预测,没有一项证实了特定的预测因素.
结论:
- 目前存在的数据不足以建立可靠的预测标记在青春期前或青春期人口的AN发作.
- 未来的前性研究应该调查更大的青春期前群体的潜在风险因素.
- 区分诱导因素和诱导因素对于有针对性的AN预防工作至关重要.
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