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在精神疾病中,大脑微血管内皮细胞和血脑屏障功能障碍在精神疾病中

Paulo Lizano1,2,3,4, Sovannarath Pong5,6,7, Stephanie Santarriaga7,8,9

  • 1Department of Psychiatry, Beth Israel Deaconess Medical Center, Boston, MA, USA. lizanopl@gmail.com.

Molecular psychiatry
|September 21, 2023
PubMed
概括

精神分裂症和双相情感障碍的血脑屏障缺陷可能源于内在的大脑微血管内皮细胞 (BMEC) 问题,而不仅仅是外周炎症. 准TNFα和MMP1可能会改善BBB缺陷亚型的屏障功能.

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