2型糖尿病和糖尿病外围神经病变对预测握力控制的影响
Marcio Dos Santos1,2, Abdalghani Yahya3, Patricia Kluding3
1Department of Physical Therapy, Rehabilitation Science and Athletic Training, University of Kansas Medical Center, Kansas City, KS, USA. mdsantos@usa.edu.
Experimental brain research
|September 21, 2023
概括
带有神经病变的2型糖尿病会损害握力控制,特别是握力比率和延迟,增加受伤风险. 在没有神经病变的2型糖尿病中,可以保持握力控制.
科学领域:
- 神经学 神经学
- 糖尿病学 糖尿病学
- 生物力学 生物力学
背景情况:
- 2型糖尿病 (T2D) 是一种普遍的代谢障碍.
- 糖尿病外围神经病变 (DPN) 是T2D的常见并发症,影响感觉和运动功能.
- 抓地力控制障碍会影响日常活动,增加受伤风险.
研究的目的:
- 为了研究T2D和DPN在对象操纵过程中对握力控制的影响.
- 为了比较单独T2D,T2D与DPN和健康对照的个体之间的握力控制变量.
主要方法:
- 三个年龄匹配组:T2D (n=11),T2D与DPN (n=13) 和健康对照组 (n=12).
- 测量了握力控制变量:握力比率 (GFR),延迟1,延迟2,时间延迟和静态力.
- 统计分析包括单向ANOVA和克鲁斯卡尔-瓦利斯测试,并进行后期比较.
主要成果:
- 群体之间观察到GFR和延迟1的显著差异.
- 与T2D单独和健康对照相比,与DPN组一起的T2D表现出更大的GFR和更长的潜伏时间1.
- 两组之间没有发现延迟2,时间延迟或静态力的显著差异.
结论:
- 在T2D患者中,DPN显著损害了握力控制 (GFR,延迟1).
- 时间延迟似乎保留了,这表明特定的运动控制缺陷.
- 患有T2D和DPN的个体可能面临更高的手部疲劳和受伤的风险,原因是握力变化.
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