在移植接受者中,COVID-19后的血栓栓塞并发症
Ayse Serra Artan1, Ahmet Burak Dirim2, Halil Yavuzkilic1
1Division of Nephrology, Department of Internal Medicine, Istanbul University Istanbul Faculty of Medicine, Istanbul, Turkey.
Nephrology (Carlton, Vic.)
|September 21, 2023
概括
接受脏移植的接受者在COVID-19后经历了血块的增加. 中度的COVID-19,老年和心脏病与这些血栓事件的更高风险有关.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 传染性疾病 传染性疾病
- 心脏病学 心脏病学
背景情况:
- 在一般人群中,COVID-19与血栓事件的增加有关.
- 在COVID-19后接受移植患者的血栓并发症数据有限.
研究的目的:
- 为了调查COVID-19后移植接受者的血栓性并发症的发生率.
- 在这个患者群体中确定与这些血栓事件相关的危险因素.
主要方法:
- 成年移植接受者被诊断患有COVID-19的回顾性观察性研究 (2020年3月 - 2022年6月).
- 终点:发生血栓栓塞事件.
- 在COVID-19后的随访时间中位数为10.8个月.
主要成果:
- 11.9%的幸存患者出现了血栓栓塞并发症.
- 适度的COVID-19,年龄较大和先前的心脏病是显著的危险因素.
- 血栓栓栓塞事件的发生率为每100个患者年10.9.
结论:
- 接受脏移植的人面临COVID-19后血栓栓塞并发症的风险增加.
- 需要进一步的前性研究来探索这些并发症的治疗策略.
相关概念视频
Kidney Transplant I: Introduction
14
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
14
Kidney Transplant II: Surgical Procedure
22
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
22
Kidney Transplant III: Nursing Management
23
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
23
Acute Kidney Injury IV: Diagnostic Studies and Prevention
21
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
21
Hemodialysis II: Procedure and Complications
27
DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
27
Acute Kidney Injury III: Clinical Manifestations
15
Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
15


