葡萄酒消费与癌症之间的关联:系统性审查和元分析
Maribel Lucerón-Lucas-Torres1, Iván Cavero-Redondo1,2, Vicente Martínez-Vizcaíno1,2
1Health and Social Research Center, Universidad de Castilla-La Mancha, Cuenca, Spain.
Frontiers in nutrition
|September 21, 2023
概括
适度的葡萄酒消费没有增加癌症风险,并且对几种癌症类型有潜在的保护性趋势. 这次系统性审查和元分析研究了葡萄酒.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 营养科学 营养科学
背景情况:
- 酒精消费是众所周知的各种癌症的风险因素.
- 适度的葡萄酒消费与降低癌症风险有事相关,与其他酒精饮料形成鲜明对比.
研究的目的:
- 系统地审查和元分析葡萄酒消费与癌症风险之间的关联.
- 评估关于适度葡萄酒摄入是否影响患不同类型癌症的可能性的证据.
主要方法:
- 在MEDLINE (PubMed),Scopus,Cochrane和Web of Science数据库中进行了全面的搜索.
- 采用了系统审查和元分析方法,包括聚合相对风险 (RRs) 计算和异质性评估.
- 研究质量和偏差风险使用纽卡斯尔-太华质量评估尺度进行了评估.
主要成果:
- 分析包括26项研究,其中73项研究在系统性审查中.
- 聚合的RR显示,对于妇科 (1.03),结肠直肠 (0.92) 或癌 (0.92) 没有显著的关联.
- 在包括的研究中观察到实质性的异质性.
结论:
- 这项研究没有发现葡萄酒消费与整体癌症风险之间存在关联的证据.
- 葡萄酒消费在胰腺癌,皮肤癌,肺癌和脑癌方面有着保护性的趋势.
- 需要进一步的研究来澄清适度葡萄酒摄入量与特定癌症类型之间的细微关系.
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