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通过整合RNA测序数据用于变体调用,改善了新抗原预测

Bui Que Tran Nguyen1, Thi Phuong Diem Tran1, Huu Thinh Nguyen2

  • 1Medical Genetics Institute, Ho Chi Minh, Vietnam.

Frontiers in immunology
|September 21, 2023
PubMed
概括

将RNA测序 (RNAseq) 与DNA测序 (DNAseq) 整合起来,可以改善癌症免疫疗法的新抗原发现. 这种方法可以识别出更高的免疫性新抗原,增强个性化的治疗策略和患者的生存率.

关键词:
新抗原优先级的确定.RNA测序 (RNAseq) 是指RNA的测序.癌症免疫疗法免疫疗法大肠直肠癌 (CRC) 是一种癌症.新抗原是一种新抗原.新抗原鉴定工作流程瘤变异的调用变体

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