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不同激活的B细胞发展调控表型,并表现出不同的免疫抑制特征:一项比较研究

Elina A Zheremyan1, Alina S Ustiugova1, Aksinya N Uvarova1

  • 1Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.

Frontiers in immunology
|September 21, 2023
PubMed
概括

为治疗产生调节性B细胞 (Bregs) 是具有挑战性的,因为数量很少. 一个CD40L + CpG + IL21组合有效地诱导免疫抑制的Bregsex vivo对于潜在的细胞治疗应用.

关键词:
布雷格诱导 活体外的活体收养的 布雷格转移免疫反应调节 免疫反应调节免疫抑制是一种免疫抑制.这就是为什么mBregs.主要的B细胞激活监管性B单元格的监管性B单元格tBregs 的时间.

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