里斯比里对自闭症谱系障碍患者认知的影响:系统性审查
Jhenelle Hutchinson1, Oluwa Folawemi2, Parikshit Bittla3
1Psychiatry, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Cureus
|September 21, 2023
概括
里斯佩里有效地治疗自闭症谱系障碍 (ASD) 的核心和非核心症状. 虽然体重增加是常见的副作用,但需要进一步的研究来探索其认知效应和长期影响.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 药理学 药理学是指药理学的学科.
背景情况:
- 自闭症谱系障碍 (ASD) 包括自闭症,阿斯伯格综合征和普遍发育障碍.
- 核心特征包括受损的社交互动,沟通缺陷和受限制的行为.
- 非核心症状包括侵略性,自我伤害和发.
研究的目的:
- 审查RISPERIDONE在治疗ASD症状中的有效性和安全性.
- 为了探索RISPERIDONE对ASD患者认知功能的影响.
主要方法:
- 对评估RISPERIDONE效应的受控试验的系统审查.
- 利用各种行为评级尺度来评估症状变化.
- 评估了RISPERIDONE的安全性,疗效,可接受性和耐受性.
主要成果:
- 里斯佩里在治疗核心和非核心ASD症状方面表现出有效性.
- 体重增加是常见的,通常是轻微的,自我限制的副作用.
- 在ASD中RISPERIDONE的认知效应需要进一步研究.
结论:
- 里斯佩里是治疗ASD症状的可行的治疗选择.
- 需要进一步研究更大的样本大小和更长的持续时间,才能充分了解瑞斯佩里在ASD治疗中的作用,特别是其认知影响.
相关概念视频
01:19Autism Spectrum Disorder
121
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
121
01:26Modeling in Therapy
114
Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
114
01:28Psychosis and Antipsychotic Drugs: Overview
307
The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
307
01:26Psychosis: Goals of Pharmacotherapy
158
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
158
01:21Antipsychotic Drugs: Therapeutic Uses and Side Effects
249
Antipsychotic drugs primarily block dopamine and serotonin receptors and cholinergic, adrenergic, and histaminergic receptors, thereby reducing hallucinations and delusions in conditions like schizophrenia. However, they can trigger unwanted extrapyramidal effects such as dystonias, Parkinson-like symptoms, and tardive dyskinesia.
Despite these side effects, antipsychotics are used therapeutically for various purposes, including managing schizophrenia, preventing nausea and vomiting, curbing...
Despite these side effects, antipsychotics are used therapeutically for various purposes, including managing schizophrenia, preventing nausea and vomiting, curbing...
249
01:30Attention-Deficit/Hyperactivity Disorder
85
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
85