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Updated: Jul 16, 2025

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作为一种新型的免疫调节剂,ICOS/ICOSL相互作用的第一类小分子抑制剂作为一种新型的免疫调节剂

Somaya A Abdel-Rahman1,2, Katarzyna Świderek3, Moustafa T Gabr1

  • 1Department of Radiology, Molecular Imaging Innovations Institute (MI3), Weill Cornell Medicine New York NY 10065 USA mog4005@med.cornell.edu.

RSC medicinal chemistry
|September 21, 2023
PubMed
概括

研究人员开发了一种新的测定方法,以找到准ICOS/ICOSL通路的小分子,这在T细胞淋巴瘤和免疫抑制中至关重要. AG-120-X成为了一种有前途的第一类抑制剂,为新的癌症疗法铺平了道路.

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