非常早期发作的产周便秘:它可以是牛奶蛋白质过敏吗?
Rajalakshmy Arakoni1, Hebat Kamal2, Sam Xianjun Cheng3
1Department of Pediatrics, University of Florida Shands Children's Hospital, Gainesville, FL 32608, United States.
World journal of gastroenterology
|September 21, 2023
概括
产周便秘可能是牛奶蛋白过敏 (CMPA) 的信号,这是一个经常被忽视的原因. 早期诊断和饮食改变可以缓解症状,从而避免对赫施普隆病等疾病进行侵入性测试.
科学领域:
- 儿科 儿科 儿科
- 过敏 免疫学 免疫学
- 胃肠病学 胃肠病学
背景情况:
- 在新生儿中延迟的 meconium 通过或便秘往往会促使对严重疾病的调查,如赫施普朗格病 (HD) 和 meconium ileus.
- 诊断HD通常需要侵袭性手术,如门测量或直肠吸血活检.
- 牛奶蛋白过敏 (CMPA) 是一种常见的婴儿疾病,但由于在子宫内接触过敏原,症状可以从出生开始表现出来.
研究的目的:
- 探索牛奶蛋白过敏 (CMPA) 是围产便秘的非典型原因.
- 为CMPA诱导的产周便秘提出非侵入性诊断和管理策略.
- 评估在周围便秘病例中避免侵入性检测的可能性.
主要方法:
- 关于新生儿中CMPA呈现的文献综述.
- 对CMPA非典型表现的分析,重点是便秘.
- 讨论饮食消除作为诊断和治疗工具.
主要成果:
- CMPA可以不典型地表现为产周便秘,而不是典型的症状,如腹或血.
- 母亲通过饮食接触牛奶蛋白可能导致子宫内敏感化和婴儿的早期症状.
- 通过饮食消除牛奶蛋白质可以导致患病婴儿的症状迅速改善.
结论:
- 在围产性便秘的差异诊断中应考虑CMPA.
- 针对CMPA的非侵入性饮食修改为新生儿便秘的某些病例提供了侵入性检测的安全替代方案.
- 实施优先排除CMPA的诊断途径可以防止不必要的侵入性手术.
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