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Updated: Jul 16, 2025

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由UBC13介导的模板切换促进了FBH1缺乏细胞中的复制应激抵抗

Alexandra L Hawks1, Amy Bergmann1, Tyler J McCraw1

  • 1Department of Genetics and Biochemistry, Clemson University, Clemson University.

bioRxiv : the preprint server for biology
|September 21, 2023
PubMed
概括

FBH1蛋白调节模板切换,以确保细胞对复制应激做出反应. 在FBH1缺乏细胞中抑制RAD51或UBC13恢复了这种反应,这表明FBH1促进了对DNA损伤的敏感性.

关键词:
在FBH1中,FBH1是FBH1.在RAD51中使用RAD51.在 UBC13 中,UBC13 是复制压力是复制的压力.模板切换的切换模式

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