视网膜病变与接受腹腔透析的患者的认知功能受损有关
Jinlan Liao1,2, Qijie Wei3, Yingying He2
1Department of Nephropathy, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Renal failure
|September 21, 2023
概括
视网膜病变在腹透析 (PD) 患者中很常见,并与认知障碍有关. 这表明对视网膜病变的查可能有助于识别面临认知衰退风险的个体.
科学领域:
- 眼科医生 眼科 眼科
- 腎臟病學 (nephrology) 是一種醫學.
- 神经学 神经学
背景情况:
- 之前的研究表明,在各种人群中,视网膜病变和认知功能之间存在联系.
- 在接受腹腔透析 (PD) 的患者中,视网膜病变和认知障碍之间的关系的数据有限.
研究的目的:
- 在PD患者中调查视网膜病变和认知障碍之间的关联.
- 探索视网膜微血管特征及其与该人群认知功能的相关性.
主要方法:
- 一项观察性,横截面研究,涉及107名患有PD的患者.
- 使用数字化照片评估视网膜的微血管特征 (扭曲,碎形尺寸,口径) 和视网膜病变 (出血,微动脉瘤).
- 使用修改型迷你精神状态检查 (3MS) 评估全球认知功能.
主要成果:
- 视网膜病变,视网膜出血和小动脉瘤的患病率分别为43%,25%和30%.
- 在调整混因素后,视网膜病变与3MS得分有负相关性 (回归系数: -3.71,p=0.03).
结论:
- 视网膜病变在PD患者中普遍存在,并与全球认知障碍相关.
- 视网膜查可以作为一种有价值的工具来识别患有认知衰退风险的PD患者.
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