运动的时间优化以降低禁食葡萄糖水平
Jill A Kanaley1, J W Porter1, N C Winn2
1Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, Missouri, USA.
The Journal of physiology
|September 21, 2023
概括
运动可以帮助管理患有肥胖和禁食葡萄糖 (OB+IFG) 损害的个体的血糖水平. 虽然运动会延迟夜间葡萄糖的升高,但它不会影响早晨的禁食葡萄糖或改善胰岛素同步.
科学领域:
- 代谢健康 代谢健康
- 时间生物学 时间生物学
- 运动生理学 运动生理学
背景情况:
- 胰岛素抵抗和2型糖尿病与昼夜节律障碍有关.
- 葡萄糖耐受性表现出白天的变化,在早上耐受性更好.
- 骨肌肉在胰岛素抵抗中起着关键作用,特别是在葡萄糖耐受性受损时.
研究的目的:
- 研究运动时间对晚上和夜间葡萄糖度的影响.
- 为了比较这些非肥胖个体与正常的禁食葡萄糖和肥胖个体的禁食葡萄糖受损的影响.
- 评估早晨和晚上运动对葡萄糖和胰岛素动态的影响.
主要方法:
- 使用了三种研究条件:没有运动 (NOEX),早晨运动 (AMEX; 0700h) 和晚上运动 (PMEX; 2000h).
- 参与者包括非肥胖者 (Non-Ob) 和肥胖者 (OB+IFG) 的人.
- 血液样本从17:40h到07:00h收集,并测量了早晨内源葡萄糖产量 (EGP).
主要成果:
- 在OB+IFG个体中,葡萄糖度在晚餐后升高,并持续了一夜,与OB和非OB组不同.
- 与NOEX相比,AMEX和PMEX都延迟了OB+IFG个体的晚上葡萄糖升高.
- 在OB+IFG个体中,运动没有改变早晨的禁食葡萄糖水平,也没有改善葡萄糖-胰岛素同步;晚上炼显示出轻微的优势.
结论:
- 运动,无论时间如何,都可以减轻肥胖和禁食葡萄糖受损的成年人的夜间葡萄糖增加.
- 在这个人群中,运动时间不会使早晨的禁食葡萄糖正常化,也不会改善受损的葡萄糖-胰岛素关系.
- 晚上炼可能比早上炼在抑制夜间葡萄糖升高方面提供了微不足道的好处.
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