喉肌 Amyloidosis:粉样气道中心23年的经验
Lauren F Tracy1,2, D O'Neil Danis2, Timothy Rodriggs1
1Department of Otolaryngology-Head and Neck Surgery, Boston University Aram V. Chobanian & Edward Avedisian School of Medicine, Boston, Massachusetts, U.S.A.
The Laryngoscope
|September 21, 2023
概括
局部化喉 Amyloidosis (LA) 是罕见的,影响声音和呼吸. 手术是首要的,但放射治疗可能有利于下喉/气管病例,而观察适合轻度症状.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 罕见疾病 罕见疾病
- 医疗治疗 医疗治疗
背景情况:
- 局部化喉 Amyloidosis (LA) 是一种罕见的疾病,影响声声和呼吸.
- 关于最佳管理和长期结果的证据有限,因为它很罕见.
研究的目的:
- 分析局部喉 Amyloidosis 的治疗方式.
- 评估影响治疗结果的患者和疾病因素.
主要方法:
- 从1999年到2022年,对71名LA患者进行了回顾性横截面分析.
- 按治疗进行分类:手术,放射治疗 (RT) 或观察.
- 对人口统计,临床表现和疾病进展的评估.
主要成果:
- 手术 (n=40),RT (n=11) 和观察 (n=20) 队列没有显著的人口统计差异.
- 与手术 (52%) 和观察 (52%) 相比,RT患者的 subglottic / tracheal amyloid (90%) 的比率更高.
- 手术和RT患者需要更多的干预,随访时间更长.
结论:
- 选择性手术是LA的主要治疗方法,可能需要多次手术.
- 观察适用于症状最小的患者.
- 放射治疗对复发性疾病,特别是 subglottic/tracheal amyloid,可能有好处.
相关概念视频
Trachea
2.2K
The trachea, commonly known as the windpipe, is a vital part of the human respiratory system. It serves as a passageway for air to travel between the larynx and the bronchi, allowing oxygen to reach the lungs. Let's explore its anatomical features, dimensions, layers of the tracheal wall, associated muscles, and the functions of its parts.
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of...
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of...
2.2K
Tracheostomy Care II: Procedure
231
Tracheostomy care is an essential nursing skill that involves cleaning and maintaining a tracheostomy tube to prevent infection and other complications. Here's a step-by-step guide explaining each procedure with its rationale. Note that disposable gloves are to be worn at all times and changed as often as needed to maintain a sterile work environment, and to protect both patient and healthcare worker.
Step 1: Perform hand hygiene, and put on personal protective equipment: gown, gloves, mask...
Step 1: Perform hand hygiene, and put on personal protective equipment: gown, gloves, mask...
231
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques
19
Airway management is essential in emergency and surgical medicine, ensuring ventilation and oxygenation in patients who cannot maintain their own airway. Clinicians use a range of techniques and devices to secure the airway, depending on the patient’s condition and the clinical context. Key methods include endotracheal intubation, rapid sequence intubation (RSI), supraglottic airway devices, and advanced visualization aids. In cases where these approaches fail, surgical airway...
19
Asthma-III: Symptoms and Complications
2.5K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
2.5K
Tracheostomy: Procedure and Tubes
700
A tracheostomy is a surgical procedure that creates an artificial opening into the trachea, typically at the second or third cartilaginous ring level. This opening allows the insertion of a tracheostomy tube, which can replace an endotracheal tube, provide mechanical ventilation, bypass an upper airway obstruction, or remove accumulated tracheobronchial secretions.
Tracheostomy tubes can be made of semiflexible plastic (polyurethane or silicone), rigid plastic, or metal, and they come in...
Tracheostomy tubes can be made of semiflexible plastic (polyurethane or silicone), rigid plastic, or metal, and they come in...
700
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.5K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.5K


