没有阿片类药物的皮肤穿神经解剖术:初步经验
Raymond Khargi1, Alan J Yaghoubian2, Ryan M Blake2
1Department of Urology, Icahn School of Medicine, New York, NY, USA. raymond.khargi2@mountsinai.org.
World journal of urology
|September 21, 2023
概括
这项研究发现,基托洛拉克是一种非阿片类药物,在皮肤透神经切除术 (PCNL) 后的疼痛控制中与氧化-乙氨基一样有效. 这种非阿片类药物的方法可以减少与阿片类药物处方相关的风险.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 疼痛管理 疼痛管理
- 公共卫生 公共卫生
背景情况:
- 阿片类药物流行是一个主要的美国公共卫生危机.
- 皮肤穿神经切除术 (PCNL) 传统上需要阿片类药物治疗疼痛.
- 医生过度处方阿片类药物有助于疫情.
研究的目的:
- 评估PCNL患者非阿片类药物疼痛治疗方案的可行性.
- 评估在没有阿片类药物的情况下出院的PCNL患者的术后结果.
- 在PCNL后的疼痛管理中减少阿片类药物消费.
主要方法:
- 对接受基托洛拉克 (NSAID) 和氧化-乙氨基 (NARC) 的PCNL患者进行了回顾性比较.
- 分析了人口,手术和术后因素.
- 主要结局:无计划的与疼痛相关的医疗保健接触. 二次结果:非疼痛经历,再入院,救援药物,并发症.
主要成果:
- 在NSAID和NARC组之间,无计划的与疼痛相关的遭遇没有显著差异 (11.4%对14.3%).
- 在NARC组中,有更多的无计划电话 (60%对34.3%).
- 之前的石头手术是PCNL后疼痛相关遭遇的唯一独立预测因素.
结论:
- 凯托洛拉克是一种可行的非阿片类药物替代品,用于PCNL后的疼痛管理.
- 非阿片类药物途径可以减轻阿片类药物风险,而不会影响止痛作用.
- 需要进一步的前性研究来确认可行性.
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