一个认知行为数字健康干预在青少年状细胞疾病的疼痛:一个随机的,受控的,多中心试验
Tonya M Palermo1,2, Chitra Lalloo3,4, Chuan Zhou2,5
1Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, United States.
Pain
|September 21, 2023
概括
一个数字认知行为疗法计划 (iCC-SCD) 在患有状细胞疾病 (SCD) 的青少年中显著降低了疼痛强度和疼痛日. 这种干预措施对管理SCD疼痛和改善应对策略有希望.
科学领域:
- 青少年健康 青少年健康
- 疼痛管理 疼痛管理
- 数字治疗学数字治疗学
背景情况:
- 状细胞疾病 (SCD) 经常导致严重的急性和慢性疼痛,导致残疾和高医疗费用.
- 心理社会干预,包括认知行为策略,对于青少年的疼痛管理是有效的.
- 这些干预措施的数字化交付为管理慢性疾病提供了一种可扩展的方法.
研究的目的:
- 与教育对照组相比,评估数字认知行为疗法 (iCanCope with Sickle Cell Disease; iCC-SCD) 计划的有效性.
- 评估iCC-SCD对SCD青少年疼痛强度,疼痛频率和应对机制的影响.
- 确定iCC-SCD在改善与SCD疼痛相关的心理社会结果方面的有效性.
主要方法:
- 一个多站点随机对照试验,涉及111名患有SCD的青少年 (12-18岁).
- 参与者被随机分配到iCC-SCD数字程序或教育对照组.
- 结局,包括疼痛强度和有疼痛的日子,在基线和6个月后期进行了评估.
主要成果:
- 与对照组相比,ICC-SCD组的青少年在6个月的随访期显示,平均疼痛强度显著降低 (b = -1.32,P = 0.009).
- 在6个月的随访中,iCC-SCD组经历的疼痛天数较少 (事件率比率=0.63,P=0.006).
- 在应对尝试,瞬间情绪和疲劳方面也观察到显著的改善.
结论:
- 数字认知行为治疗计划 (iCC-SCD) 有效地降低了状细胞疾病青少年的疼痛强度和频率.
- iCC-SCD显示出作为一种有价值的工具,可以提高患有SCD的年轻人疼痛管理和应对技能的潜力.
- 需要进一步的研究来优化实施战略,将基于证据的数字疗法整合到SCD护理环境中.
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