相关实验视频

Updated: Jul 16, 2025

Use of Primary Cultured Hippocampal Neurons to Study the Assembly of Axon Initial Segments
06:53

Use of Primary Cultured Hippocampal Neurons to Study the Assembly of Axon Initial Segments

Published on: February 12, 2021

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指定器官横向性的Bicc1核糖蛋白复合体通过ANKS6诱导的相关ANKS3的结构改造获得许可

Benjamin Rothé1, Yayoi Ikawa2, Zhidian Zhang3

  • 1Ecole Polytechnique Fédérale de Lausanne (EPFL) SV ISREC, Lausanne, Switzerland.

PLoS biology
|September 21, 2023
PubMed
概括

一项新的研究揭示了ANKS3蛋白切割如何破坏Dand5mRNA衰变,导致对称衰变和潜在的横向性缺陷. 这一发现揭示了一种调节Bicaudal-C1 (Bicc1) 核糖核粒子形成的新机制.

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Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development09:32

Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development

Published on: June 15, 2017

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Horizontal Gel Electrophoresis for Enhanced Detection of Protein-RNA Complexes06:36

Horizontal Gel Electrophoresis for Enhanced Detection of Protein-RNA Complexes

Published on: July 28, 2017

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Mechanism of Filopodia Formation01:39

Mechanism of Filopodia Formation

Filopodia are thin, actin-rich cellular protrusions that play an important role in many fundamental cellular functions. They vary in their occurrence, length, and positioning in different cell types, suggesting their diverse roles.
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Restarting Stalled Replication Forks02:37

Restarting Stalled Replication Forks

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Disassembly of Intermediate Filaments

Intermediate filaments (IFs) do not undergo spontaneous disassembly. Enzymes, kinases, and phosphatases add and remove phosphates from specific sites to regulate their disassembly. The IF concentration in the cytoplasm also regulates the disassembly. If the concentration crosses a threshold, it activates the protein kinases in the vicinity, allowing the phosphorylation of IFs.
Keratin proteins, found at the cell periphery near cell junctions, undergo a cycle of assembly and disassembly. In Type...
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Cytoskeletal Coordination in Cell Migration01:32

Cytoskeletal Coordination in Cell Migration

A migrating cell changes its shape during the cyclic events of attachment and detachment from the substratum and repositions the cell organelles correspondingly. These complex events are orchestrated by the dynamic cytoskeletal network comprising actin filaments, intermediate filaments, and microtubules. Cytoskeletal crosstalk — the direct and indirect communication between the different components — is crucial for this coordination. Direct communication involves various linker...
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Cell Motility through Blebbing

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Blebbing Through the Matrix
In multicellular...
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