保护所有人免受破伤风的道路
Md Abdullah Saeed Khan1,2, Mohammad Jahid Hasan1, Mohammad Delwer Hossain Hawlader3
1Tropical Disease and Health Research Centre, Dhaka, Bangladesh.
PLoS neglected tropical diseases
|September 21, 2023
概括
结核病在低收入和中等收入国家仍然是一个重要的公共卫生问题,特别影响成年男性,原因是报告不足和有限的重症监护服务. 有针对性的疫苗接种策略对于保护至关重要.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 在低收入和中等收入国家 (LMICs) 中,结核病仍然是一个主要的公共卫生问题.
- 尽管全球接种疫苗的努力,在某些地区仍然存在大量的病例和死亡人数.
- 由于监测和报告系统不充分,成年人风往往被报告不足.
研究的目的:
- 为了突出疹对成年男性的不成比例影响.
- 强调病例管理的挑战,包括重症监护的准入和高死亡率.
- 倡导加强风预防策略.
主要方法:
- 对LMIC中病发病率,报告率和病例死亡率的现有文献的审查.
- 对风影响的人口统计数据的分析.
- 评估当前的疫苗接种计划和重症监护服务的可用性.
主要成果:
- 成年人结石风的死亡率很高,严重的原因是无法获得重症监护,特别是呼吸机支持.
- 与妇女和儿童相比,男性受到破伤风的影响不成比例.
- 现有的免疫策略有效地保护妇女和儿童,但成年男性的疫苗接种覆盖率不足.
结论:
- 需要加强对成年人结节炎的监测和报告.
- 改善对重症监护服务的准入对于降低破伤风死亡率至关重要.
- 促进符合条件的儿童和青少年男孩的复发疫苗接种,以及脆弱职业的成年人进行破伤风免疫接种,对于全面防治破伤风至关重要.
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