人类在高海拔地区的听觉功能. 一个范围审查审查.
Michela Masè1,2, Andrea Viziano3, Giacomo Strapazzon1
1Institute of Mountain Emergency Medicine, Eurac Research, Bolzano, Italy.
PloS one
|September 21, 2023
概括
高空暴露似乎会降低听觉功能,影响听觉值和响应. 需要使用标准化方法进行进一步的研究,以了解这些内耳变化.
科学领域:
- 身体生理学 身体生理学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 航空航天医学 航空航天医学
背景情况:
- 高海拔 (HA) 环境带来了独特的生理挑战.
- 对于HA对内耳和听觉功能的影响仍然不完全理解.
- 众所周知,感官器官的反应受到HA的影响,需要对听觉通路进行调查.
研究的目的:
- 系统地审查和综合现有证据,关于高海拔暴露对内耳的影响.
- 专注于健康个体暴露在高海拔地区的听觉功能的变化.
- 确定当前关于HA和听觉的研究中的差距.
主要方法:
- 根据PRISMA-ScR指南进行了范围审查.
- 在PubMed,Scopus和Web of Science数据库中进行了系统的搜索.
- 包括在过去20年内发表的研究,量化HA健康受试者的听觉功能.
主要成果:
- 分析了17项涉及888名受试者的研究,大多数研究报告听觉功能下降.
- 常见的发现包括听觉值升高,听觉唤起响应 (AER) 延长的延迟时间,以及减少的耳声排放 (OAE).
- 研究方案,HA暴露高度和持续时间存在显著的异质性.
结论:
- 高空暴露与可测量的听觉功能下降有关.
- 观察到的变化包括听力值,AER和OAE的变化.
- 为明确病理生理学影响,建议在未来的研究中采用标准化方案和较大的研究群体.
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