所谓的带动脉 (ligamentum arteriosum) 被内置在内
1Department of Clinical Anatomy, Faculty of Health and Medicine, Lancaster University, Lancaster, United Kingdom.
PloS one
|September 21, 2023
概括
血管带保留了胎儿生命中的内化,这与以前的观点相反. 这一发现表明神经活动在调节血液流动和周围组织方面可能发挥作用.
科学领域:
- 心血管生物学 心血管生物学
- 神经科学是一个神经科学.
- 发展生物学 发展生物学
背景情况:
- 动脉管是胎儿血管,绕过肺部.
- 在产后,它转化为带动脉 (LA).
- 管道动脉管的内化已知,但其在LA的持续性尚不清楚.
研究的目的:
- 为了调查结节动脉是否在出生后保持内置.
- 在人类和动物模型中描述这种内化的性质.
主要方法:
- 使用神经元标记物 (PGP 9.5) 和光滑肌肉标记物 (光滑肌肉活性物) 进行双免疫光标记.
- 在小鼠LA样本上进行传输电子显微镜 (TEM).
- 对人类,猪和老鼠的LA组织进行分析.
主要成果:
- 在小鼠,猪和老年人中证实了带动脉的广泛内化.
- 免疫标记显示了强烈的神经元标记物的存在.
- TEM揭示了靠近光滑肌肉细胞的神经末,比通常在弹性动脉中看到的更近.
结论:
- 血管带被内化,类似于胎儿的血管通道.
- 这种内化可能会影响船舶的合规性和当地的微观环境.
- 对LA内化神经化学的进一步研究是必要的.
相关概念视频
The Arch of Aorta
726
The coronary arteries, originating from the ascending aorta, bifurcate from two sinuses located within the ascending aorta. Positioned just above the aortic semilunar valve, these sinuses house essential aortic baroreceptors and chemoreceptors, crucial for maintaining cardiac function. The left coronary artery and the right coronary artery branch off from the left posterior and anterior aortic sinuses, respectively.
Encircling the heart, the coronary arteries form a ring-like structure before...
Encircling the heart, the coronary arteries form a ring-like structure before...
726
Arteries and Arterioles
4.3K
Arteries, the vasculature responsible for transporting blood from the heart, possess robust walls capable of enduring the elevated pressures exerted by the heartbeat. Arteries near the heart are especially thick-walled and enriched with elastic fibers across their three tunics, classifying them as elastic or conducting arteries. These arteries, usually with a diameter exceeding 10 mm, are characterized by their ability to dilate in response to the blood pumped from the heart's ventricles...
4.3K
Arteries of Lower Limbs
1.6K
The external iliac artery transitions out of the body cavity, entering the femoral region of the lower leg, and is renamed the femoral artery at the point where it traverses the body wall. This artery is responsible for the distribution of blood to the thigh's deep muscles and the skin's ventral and lateral regions, achieved through several minor branches and the lateral deep femoral artery, which also spawns a lateral circumflex artery. The knee area receives blood from the genicular...
1.6K
Blood and Nerve Supply to the Kidney
1.2K
The kidneys are vital organs responsible for filtering and cleaning blood, removing waste products, and regulating electrolyte levels. To perform these essential functions, they require a constant and robust blood supply.
Bloody Supply to the Kidneys:
The kidneys receive their blood supply from the renal arteries, which branch off from the abdominal aorta—the main artery supplying the abdomen and lower body. The renal arteries enter the kidneys at the hilum, a notch on the medial side of...
Bloody Supply to the Kidneys:
The kidneys receive their blood supply from the renal arteries, which branch off from the abdominal aorta—the main artery supplying the abdomen and lower body. The renal arteries enter the kidneys at the hilum, a notch on the medial side of...
1.2K
Gross Anatomy of the Lungs
1.9K
The lungs are a pair of vital organs connected to the trachea via the left and right bronchi. The base of these organs meets the dome-shaped muscle known as the diaphragm. Encased by the pleurae, the lungs contact the mediastinum. The right lung is shorter yet wider, and has a larger volume than the left lung. The left lung has an indentation known as the cardiac notch. The superior region of the lungs is referred to as the apex, whereas the base is the lower region near the diaphragm. The...
1.9K
Arteries of the Head and Neck
1.4K
The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
1.4K


