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Updated: Jul 16, 2025

Tyramide Signal Amplification for the Immunofluorescent Staining of ZBP1-Dependent Phosphorylation of RIPK3 and MLKL After HSV-1 Infection in Human Cells
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Tyramide Signal Amplification for the Immunofluorescent Staining of ZBP1-Dependent Phosphorylation of RIPK3 and MLKL After HSV-1 Infection in Human Cells

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TAK1的小分子激活剂促进其活动依赖的泛化和 TRAIL介导的瘤细胞死亡

Weimin Sun1, Guowei Wu1, Xinyu Tian1

  • 1Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201203, China.

Proceedings of the National Academy of Sciences of the United States of America
|September 21, 2023
PubMed
概括

小分子R406/R788激活TAK1 (转化生长因子激活激酶1),增强RIPK1-依赖的细胞死亡. 这些TAK1激活剂通过促进持续的TAK1和RIPK1激活来增强基于TRAIL的癌症疗法.

关键词:
在RIPK1中使用.这就是TAK1的意义.细胞死亡,细胞死亡.

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