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美国成年人睡眠时间和甲状腺功能之间的关系:NHANES 2007-2012年
Mingzheng Wang1, Xiaofeng Lu1, Xiaogang Zheng1
1Department of Breast and Thyroid, Jinhua Central Hospital, Jinhua, Zhejiang, China.
PloS one
|September 21, 2023
概括
较短的睡眠时间与较低的自由三甲状腺素 (FT3) 水平有关. 这种关联随着睡眠时间接近推的健康数量而减少,这表明甲状腺功能的值效应.
科学领域:
- 内分泌学 在内分泌学.
- 睡眠医学 睡眠医学
- 公共卫生 公共卫生
背景情况:
- 睡眠障碍影响了相当一部分人口,并可能对健康产生影响.
- 睡眠时间和甲状腺功能之间的关系尚未得到充分证实.
- 甲状腺激素在调节新陈代谢和整体健康方面发挥着至关重要的作用.
研究的目的:
- 研究美国成年人睡眠时间和甲状腺功能标志物之间的关联.
- 确定睡眠时间是否影响甲状腺刺激激素 (TSH),自由T3 (FT3) 和自由T4 (FT4) 水平.
- 为了确定睡眠时间的潜在门,影响甲状腺功能.
主要方法:
- 利用了NHANES 2007-2012数据集中的8102名参与者的数据.
- 采用加权数据分析,包括线性回归与光滑曲线拟合.
- 进行了分层分析,以探索不同睡眠时间之间的关联.
主要成果:
- 在未经调整的分析中,增加睡眠时间与更高的TSH和更低的FT3水平有关.
- 睡眠时间和FT3之间存在显著的负面关系,睡眠时间为7小时或更短.
- 没有注意到FT3的显著变化,睡眠时间进一步增加超过7小时.
结论:
- 睡眠时间与FT3水平相反,特别是在更短的睡眠时间.
- 睡眠时间对FT3的负面影响在7小时睡眠以下是最明显的.
- 获得足够的睡眠时间 (大约7小时) 似乎可以减轻与FT3水平的相关性.
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