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相关概念视频

Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

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Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
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Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

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Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
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Mitral Regurgitation I: Introduction01:20

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Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
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Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

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Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
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Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

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The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
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相关实验视频

Updated: Jul 16, 2025

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
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超正常的左心室功能

Ryohei Ono1, Luiz Menezes Falcão2

  • 1Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.

The American journal of cardiology
|September 21, 2023
PubMed
概括
此摘要是机器生成的。

心力衰竭与超正常喷射率 (HFsnEF) 是一个新提出的HF类别. 本综述探讨了它的定义,病理生理学和预后,强调了潜在的风险和独特的患者特征.

关键词:
HFpEF HFpEF 的意思是什么心脏衰竭是因为心脏衰竭.左心室喷射分数的部分.超正常的超正常的

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Last Updated: Jul 16, 2025

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
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Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
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科学领域:

  • 心脏病学 心脏病学
  • 心脏衰竭研究研究

背景情况:

  • 心力衰竭 (HF) 通常根据左心室喷射率 (LVEF) 分类.
  • 提出了一种新的HF分类,HF具有超正常射出分数 (HFsnEF) (LVEF>65%) 的HF.
  • 现有数据表明,HFsnEF可能与增加的不良心血管事件和U形死亡率有关.

研究的目的:

  • 系统地审查关于患有超正常 LV 功能的患者的现有文献.
  • 定义HFsnEF,阐明其拟议的病理生理学,确定表型,并概述诊断策略.
  • 为了巩固目前对HFsnEF预后的理解.

主要方法:

  • 系统性文献综述对患有超正常 LV 功能的患者的研究.
  • 对有关HFsnEF定义,病理生理学,表型,诊断和预后的报告数据的分析.

主要成果:

  • HFsnEF在女性中更为常见,并且与非胰岛素HF,较高的BUN,较低的尿素和较少的β-阻断剂使用有关.
  • 病理生理学可能涉及微血管功能障碍,炎症,冠状动脉流量储备减少,低中风体积指数,较小的心室和集中式LV几何.
  • 预后似乎与长期重大心血管不良事件的风险增加有关.

结论:

  • HFsnEF代表了一个独特的HF表型,具有独特的特征和潜在风险.
  • 需要进一步的研究,以充分确定HFsnEF的预后和最佳管理.
  • 了解HFsnEF对于准确诊断和特定患者群体的风险分层至关重要.