信号诱导的miRNAs系统抑制揭示了癌症的脆弱性和向治疗的敏感性

Alexander A Wurm1, Silke Brilloff2, Sofia Kolovich2

  • 1Mildred Scheel Early Career Center, National Center for Tumor Diseases (NCT/UCC) Dresden, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; Department of Translational Medical Oncology, National Center for Tumor Diseases (NCT/UCC) Dresden, a partnership between DKFZ, Faculty of Medicine of the Technische Universität Dresden, University Hospital Carl Gustav Carus Dresden, and Helmholtz-Zentrum Dresden - Rossendorf (HZDR), Dresden, Germany; Translational Medical Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; German Cancer Consortium (DKTK), Dresden, Germany.

Cell reports. Medicine
|September 21, 2023
PubMed
概括

这项研究通过分析微RNA (miRNA) 表达方式来确定癌症的脆弱性. 一种新的方法使用低miRNA签名来找到可用药的点,改善癌症治疗预测.

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