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Updated: Jul 16, 2025

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
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一个以SMAD3表达为中心的负反循环,用于转化生长因子β1诱导的角膜肌纤维细胞分化

Yunlan Tang1, Enming Du1, Gang Wang1

  • 1Henan Eye Hospital, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, 450003, China.

Experimental eye research
|September 21, 2023
PubMed
概括

转化生长因子β1 (TGF-β1) 通过降低SMAD3.3的调节诱导角膜纤维化. 这种由SMAD4和p38信号调节的SMAD3降低形成了一个反循环,表明SMAD3是角膜纤维化潜在的治疗标.

关键词:
角膜肌纤维细胞的分化角膜伤口愈合的愈合方式在SMAD3中,我们可以看到SMAD3.在SMAD4中,我们可以看到SMAD4.在TGF-β1中.在p38中,p38是什么?

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