肥胖患者的骨关节炎:减肥手术对其演变的影响
Florent Eymard1, Judith Aron-Wisnewsky2
1Department of Rheumatology, Henri-Mondor University Hospital, Assistance publique-Hôpitaux de Paris, AP-HP, 1, rue Gustave-Eiffel, 94000 Créteil, France.
Joint bone spine
|September 21, 2023
概括
腹部外科手术 (BS) 可以减少骨关节炎 (OA) 疼痛和缓慢进展. 然而,它在预防长期并发症或改善关节置换手术后的结果方面提供了有限的好处.
科学领域:
- 整形外科 整形外科 整形外科
- 代谢手术 代谢手术
- 类风湿病学 类风湿病学
背景情况:
- 肥胖是骨关节炎 (OA) 的一个主要风险因素,增加疼痛和功能限制.
- 肥胖患者的关节内治疗成功率较低,并且更频繁地接受关节整形手术.
- 肥胖患者的关节整形术改善率较低,并发症率更高.
研究的目的:
- 评估减肥手术 (BS) 对骨关节炎 (OA) 症状和关节整形术后的结果的影响.
- 评估BS是否影响关节置换手术的短期和长期并发症.
- 为了确定BS在关节整形前的成本效益.
主要方法:
- 审查关于减肥手术,骨关节炎和关节整形术结果的现有文献.
- 分析了对先前患有和没有腹部外科手术的患者的关节整形结果进行比较的研究.
- 检查与减肥手术后OA进展相关的生物标志物数据.
主要成果:
- 腹腔外科手术显著减少膝盖OA患者的疼痛和功能限制.
- BS可能会减少短期和中期关节修复术并发症,但不会显著改变长期并发症率.
- 关节整形术后的功能结果没有得到之前的减肥手术显著改善.
结论:
- 腹腔外科手术可以缓解OA症状,并可能减缓疾病的进展.
- 在预防长期关节整形并发症和增强功能结果方面,BS的好处是有限的.
- 尽管临床结果不尽相同,但在关节整形之前的减肥手术被认为是具有成本效益的.
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