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使用左心室压力-应变循环来评估心肌功能在预测心力衰竭的价值与改善的射出分数

Tianyue Li¹, Ziyao Li², Shuang Guo³

¹Department of Ultrasound, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai 519000, China; Department of Ultrasound, the Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China.

International journal of cardiology

|September 21, 2023

概括

心肌工作参数,包括全球周长应变 (GCS) 和全球工作指数 (GWI),可以预测心力衰竭与改善喷射率 (HFimpEF) 在减少喷射率 (HFrEF) 的患者. 使用GCS,全局构造工作 (GCW),左心室末端透气直径 (LVEDD) 和左心室喷射率 (LVEF) 的模型显示出最佳的诊断能力.

科学领域:

心脏病学心脏病学
医疗成像医学成像
生物医学工程生物医学工程

背景情况:

减少喷射分数 (HFrEF) 的心力衰竭是一个重大的临床挑战.
确定可能改善的患者 (HFimpEF) 对于治疗策略至关重要.
超声波左心室压力-应变循环 (LV PSL) 提供了对心肌工作的见解.

研究的目的:

在HFrEF患者中使用LV PSL评估心肌工作参数.
为了将这些参数与改善 (HFimpEF) 和持续使用HFrEF的患者之间的参数进行比较.
为了确定心肌工作参数的预测值,用于HFimpEF转换.

主要方法:

120名HFrEF患者使用临床和心声回声学数据进行了分析.
使用左心室压力-应变循环 (LV PSL) 技术.
逻辑回归和ROC曲线确定了预测因素;构建了多变量模型.

主要成果:

HFimpEF患者表现出较高的缩血压,LVEF,LV GLS,GCW,GWE,GWI和较低的LVEDD.
LVEF,LVEDD,GLS,GWI和GCW是HFimpEF转换的重要预测因素.
一个包含LVEF,LVEDD,GLS和GCW的预测模型 (模型4) 显示出最佳的诊断能力.

结论:

结合GCW,LVEF,LVEDD和GLS的预测模型可以有效地预测HFimpEF.
这些心肌工作参数是HFrEF管理中的临床决策的宝贵工具.

关键词:

心声回声扫描 (Echocardiography) 是一种心声回声扫描.心力衰竭与改善的射出分数心力衰竭.心肌功能的工作.预测建模的预测建模.压力-应变循环的循环.

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