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瘤向的介质蛋白2增强了FAP导向的放射性灵配体治疗药物的抗癌活性

Andrea Galbiati1, Paulina Dorten2, Ettore Gilardoni1

  • 1Research and Development Department, Philochem AG, Otelfingen, Switzerland.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
|September 21, 2023
PubMed
概括

结合纤维细胞激活蛋白 (FAP) 向的放射性连接体与互白素-2疗法,协同消除了FAP阳性瘤. 这种组合疗法在临床前模型中通过激活自然杀手细胞,证明了瘤的完全缓解.

关键词:
组合疗法 组合疗法纤维细胞激活蛋白质的激活蛋白质免疫细胞因子 免疫细胞因子放射性链和治疗药物.瘤向向向的目标

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