腹腔透析的年轻和老年患者的比较:一项回顾性观察性研究
Erdem Çankaya1, Murat Altunok1
1Medical Faculty, Department of Nephrology, Atatürk University, Erzurum, Turkey.
Seminars in dialysis
|September 21, 2023
概括
经过腹膜透析 (PD) 的老年患者的并发症率比年轻患者低. 然而,对援助的需要是一个重要的障碍,这表明支持可能会增加PD使用在老年人中.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 老年病的医生 老年病的医生
- 内部医学 内部医学
背景情况:
- 全球预期寿命正在增加,导致老年人慢性病 (CKD) 的增加.
- 腹腔透析 (PD) 的使用在老年人群中越来越多,但仍然存在对潜在并发症的担忧.
研究的目的:
- 为了比较腹透析 (PD) 在老年患者 (≥65岁) 与年轻患者 (<65岁) 的结果.
- 确定影响老年PD患者死亡率的因素.
主要方法:
- 在一个中心接受PD的311名患者 (103名老年人,208名年轻人) 的回顾性分析.
- 人口统计数据,白蛋白水平,尿液输出,腹膜炎的发病率,第一次腹膜炎的时间,PD终点和年龄组之间的死亡率的比较.
主要成果:
- 与年轻患者相比,老年PD患者表现出较低的腹膜炎 (0.61-0.75) 和技术失败 (6.8%-23.1%) 率.
- 两组之间没有观察到无炎生存时间的显著差异 (p=0.931).
- 影响死亡率的因素包括需要帮助 (HR 2.569),第一次腹膜炎的时间 (HR 0.983),平均白蛋白 (HR 0.191) 和尿液输出 (HR 1.154).
结论:
- 与年轻的同行相比,老年PD患者在腹膜炎和技术生存方面表现出有利的结果.
- 对于老年PD患者来说,需要帮助是最大的挑战,这凸显了支持系统的重要性.
- 解决帮助需求可能会显著增加老年人群中PD的采用率.
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