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相关概念视频

The Parathyroid Glands00:59

The Parathyroid Glands

2.2K
The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
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Hormones and Bone Tissue01:17

Hormones and Bone Tissue

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The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
2.7K
Skeleton and Calcium Homeostasis01:21

Skeleton and Calcium Homeostasis

4.6K
Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
4.6K
Major Hormones and Their Functions01:27

Major Hormones and Their Functions

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Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
473
Synthesis and Functions of Calcitonin00:51

Synthesis and Functions of Calcitonin

1.9K
Calcitonin, a vital polypeptide hormone, regulates calcium levels within body fluids. It is released by the parafollicular cells, also known as C cells, situated in the follicular epithelium of the thyroid gland. Calcitonin responds to fluctuations in blood calcium levels and the influence of gastrointestinal hormones like gastrin and cholecystokinin.
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...
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Bone Disorders01:29

Bone Disorders

3.6K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
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相关实验视频

Updated: Jul 16, 2025

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
03:57

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Published on: July 14, 2023

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甲状腺功能下降症 甲状腺功能下降症

Richard Sotorník

    Casopis lekaru ceskych
    |September 21, 2023
    PubMed
    概括

    甲状腺功能低下症是一种罕见的内分泌疾病,由于偏激素缺乏,导致低. 目前的治疗方法不足,唯一的重组性偏激素药物被召回,强调需要更好的治疗方法.

    科学领域:

    • 内分泌学 在内分泌学.
    • 罕见疾病 罕见疾病

    背景情况:

    • 甲状腺功能低下症是由于副荷尔蒙缺乏导致的,导致低热血症和神经肌肉症状.
    • 传统的用和维生素D治疗有局限性,可能导致慢性并发症.
    • 唯一可用的重组性偏激素药物正在被召回,造成了治疗缺口.

    研究的目的:

    • 审查管理下甲状腺症的挑战.
    • 讨论目前治疗方法的局限性.
    • 突出有效的副荷尔蒙替代疗法的未满足需求.

    主要方法:

    • 文献综述下甲状腺症病理生理学和治疗.
    • 分析当前的治疗策略及其缺点.
    • 评估复合性偏激素药物召回的影响.

    主要成果:

    • 副荷尔蒙缺乏导致显著的神经肌肉问题.
    • 标准治疗不充分取代副激素,并带有风险.
    • 重组性偏激素的召回加剧了治疗的挑战.

    结论:

    • 低副类甲状腺症的有效管理仍然是一个临床挑战.
    关键词:
    和是最重要的.过低血症 (hypocalcemia) 的情况甲状腺过敏症 (hypoparathyroidism) 是一种严重的疾病.一个副荷尔蒙激素.酸盐酸盐的使用方法是一种的物质.维生素维生素维生素是一种维生素.维生素D是维生素D的重要组成部分.

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    Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation
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    Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation

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    Last Updated: Jul 16, 2025

    Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
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    Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
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    Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

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    Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation
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    Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation

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  • 对于新且易于获得的偏激素替代疗法有着极大的需求.
  • 判断性甲状腺切除术是预防低副甲状腺症的关键.