慢性呼吸道疾病作为疹疹感染的危险因素
Diego Morena1, Sara Lumbreras2, José Miguel Rodríguez3
1Servicio de Neumología, Hospital Universitario de Guadalajara, Guadalajara, Spain; Programa de Doctorado en Ciencias de la Salud, Universidad de Alcalá, Madrid, Spain.
Archivos de bronconeumologia
|September 21, 2023
概括
慢性呼吸道疾病如COPD,喘和肺癌增加了疹 (HZ) 和后神经疼痛 (PHN) 的风险. 疫苗接种策略应考虑这些患者群体.
科学领域:
- 流行病学 流行病学
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 疹疹 (HZ),由疹疹病毒 (VZV) 再激活引起,与各种疾病有关.
- 慢性呼吸道疾病是已知的HZ和后神经疼痛 (PHN) 的危险因素.
研究的目的:
- 确定HZ和PHN的流行率和风险因素.
- 研究HZ/PHN与常见的慢性呼吸道疾病 (COPD,喘,肺癌和OSA) 之间的关联.
主要方法:
- 观察性,回顾性,非干预性研究 (2012-2020年).
- 来自西班牙卡斯蒂利亚-拉曼查地区卫生系统的数据.
- 使用人工智能支持系统 (Savana Manager 3.0) 分析的电子病历.
主要成果:
- 确诊了31,765例HZ病例;随着50岁以上的年龄,患病率增加.
- 慢性肺炎,喘和肺癌显著增加HZ风险 (ORs 1.16-1.68),特别是在并发症时.
- 在COPD和肺癌中观察到PHN风险增加 (ORs 1.14-1.24),并发症进一步放大.
结论:
- 在临床实践中,喘,COPD和肺癌与HZ和PHN的更高风险有关.
- 这些发现强调了为患有这些呼吸系统疾病的患者考虑接种疫苗的重要性.
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