双功能的蚀刻剂同时去矿化和稳定牙,使得原蛋白能够抵抗树脂结合的降解
Saleha Nisar1, Hang Liu1, Viviane Hass1
1School of Dentistry, University of Missouri - Kansas City, Kansas City, MO 64108, USA.
Dental materials : official publication of the Academy of Dental Materials
|September 21, 2023
概括
新的双重功能蚀刻剂含有theaflavins (TF) 或葡萄提取物 (GSE) 可以同时去矿化牙和交联原. 这些新型蚀刻剂增强了牙的生物稳定性和树脂结合,提供了更好的临床性能.
科学领域:
- 生物材料科学 生物材料科学
- 牙科材料科学 牙科材料科学
- 聚合物化学 聚合物化学
背景情况:
- 登丁原蛋白的降解损害了树脂-登丁键的耐用性.
- 目前的蚀刻主要关注的是去矿化,而不是原稳定.
研究的目的:
- 开发用于同时去矿化和原稳定的双重功能蚀刻.
- 评估这些蚀刻对原交联,生物稳定性和树脂结合的影响.
主要方法:
- 用甘油酸,酸和多醇 (茶叶黄素或葡萄种子提取物) 制备的双重功能蚀刻剂.
- 使用富里埃变换红外光谱学和电子显微镜评估原蛋白交叉连接和降解阻力.
- 在热循环后评估树脂-丁丁键强度,纳米泄漏和矩阵金属蛋白酶 (MMP) 活性.
主要成果:
- 双功能蚀刻剂有效地在30秒内去矿牙,并诱导原交联.
- 与葡萄提取物相比,含有叶黄素的蚀刻剂对原酶降解提供了更好的保护.
- 与对照组不同,蚀刻剂显著提高了粘合耐用性,减少了热循环后的纳米泄漏和MMP活性.
结论:
- 双功能蚀刻剂,特别是含有茶叶黄素的蚀刻剂,为稳定牙原蛋白提供了一种有前途的方法.
- 这些蚀刻剂增强了非矿化牙基质的长期生物稳定性.
- 在具有挑战性的临床条件下,改进的原稳定导致更持久的树脂-牙键.
关键词:
纽带强度 纽带强度 纽带强度交叉连接 (crosslinking) 是一种交叉连接.牙的原蛋白是牙中的原蛋白.石版画家是什么样的人美国的FTIR是FTIR.黄类化合物 黄类化合物葡萄糖酸是什么? 葡萄糖酸是什么?矩阵金属蛋白酶是一种金属蛋白酶.更多相关视频
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