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温根TNFR通过一种非常规的机制调节FGF路径

Annalisa Letizia1, Maria Lluisa Espinàs1, Panagiotis Giannios1,2

  • 1Department of Cells and Tissues. Institut de Biologia Molecular de Barcelona, IBMB-CSIC. Parc Científic de Barcelona, Baldiri Reixac, 10-12, 08028, Barcelona, Spain.

Nature communications
|September 21, 2023
PubMed
概括

温根是一种TNFR,通过调节FGFRBreathless下游的MAPK通路来抑制气管细胞分化. 这种相互作用发生在细胞内囊泡中,表明一种新的TNFR机制.

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