妊娠期糖尿病中新生儿大脑微观结构异常,由MRI纹理分析揭示
Zhi Feng1, Yurong Zheng1, Ping Wang1
1Department of Radiology, The Affiliated Hospital of Southwest Medical University, No.23 Tai Ping Street, Luzhou, 646000, Sichuan, China.
Scientific reports
|September 21, 2023
概括
孕期糖尿病 (GDM) 影响新生儿大脑发育. 磁力共振成像纹理分析有效地识别了新生儿暴露在GDM中的这些微观结构变化.
科学领域:
- 神经成像是一种神经成像.
- 发展生物学 发展生物学
- 医学物理 医学物理
背景情况:
- 孕期糖尿病 (GDM) 是一个重要的妊娠并发症.
- 改变新生儿大脑微观结构是GDM的潜在后果.
- 需要使用非侵入性成像方法来评估这些影响.
研究的目的:
- 评估MRI纹理分析在检测新生儿大脑微观结构的GDM相关影响方面的实用性.
- 为了比较不同纹理特征组合的诊断性能.
主要方法:
- 在GDM (N=37) 和对照 (N=34) 组中的新生儿头部MRI扫描的回顾性分析.
- 使用MaZda软件进行纹理特征提取和维度减小.
- 采用最低误判率方法进行特征选择和SPSS进行统计分析.
主要成果:
- GDM显著影响新生儿大脑微观结构的发育.
- 来自不同MRI序列和大脑区域的纹理特征显示出不同的识别性能.
- 在多个MRI序列中进行的组合纹理分析表明识别精度高.
结论:
- 核磁共振成像纹理分析是评估GDM对新生儿大脑发育的影响的宝贵工具.
- 多序MRI纹理分析在识别与GDM相关的微观结构异常方面提供了高性能.
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