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容许性高头对手术内大脑氧化和早期术后认知功能的影响,在接受腹腔镜结直肠手术的老年患者中,具有非急性脆弱大脑功能:协议研究研究

Zhichao Li¹, Youzhuang Zhu², Shangyuan Qin³

¹Department of Anesthesiology, Shengjing Hospital of China Medical University, Shenyang, China.

|September 22, 2023

概括

这项研究研究了允许性高头 (PHC) 以改善老年患者的区域大脑氧和 (rSO2),旨在增强手术期间的大脑保护和认知功能.

科学领域:

麻醉学和外科手术期间的医学.
神经科学是一个神经科学.
老年医学老年医学

背景情况:

老年人的外科手术期间大脑保护是一个关键的研究领域.
监测区域大脑氧和度 (rSO2) 和实施干预措施是具有挑战性的.
近红外频谱 (NIRS) 技术提供先进的手术内rSO2监测.

研究的目的:

评估容许性头皮增大 (PHC) 对老年患者手术内rSO2的影响.
探索rSO2与术后认知功能之间的关系.
为老年手术患者的临床大脑保护策略提供指导.

主要方法:

一个单中心随机对照试验 (RCT) 涉及76名老年患者.
随机分配到对照组或干预组 (基于PHC的机械通风) 的患者.
主要结局:从基线到手术完成时rSO2的变化;次要结局:大脑氧化,脑损伤标志物,认知功能.

主要成果:

这项研究旨在揭示PHC对非急性脆弱大脑功能 (NFBF) 的老年患者手术期间rSO2的影响.
它将分析rSO2的趋势和术后认知结果的差异.
预期的发现将为临床实践和管理策略提供信息.

结论:

该试验旨在为临床政策提供有关老年患者手术期间大脑氧气监测的信息.
结果将指导大脑保护措施,并可能改善术后认知结果.
这项研究对改善老年人手术前护理和神经结果具有重要意义.

关键词:

接近红外光谱的近红外光谱没有急性脆弱的大脑功能.年龄较大的患者.在外科手术期间出现的神经认知障碍.允许性高头症是什么随机对照试验是随机对照试验.区域大脑氧和区域大脑氧和

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