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Updated: Jul 16, 2025

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该NCOR-HDAC3联合抑制复合体调节了转录因子ERG的白血病产生潜力

Eitan Kugler1,2, Shreyas Madiwale1,3, Darren Yong4,5

  • 1Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Nature communications
|September 22, 2023
PubMed
概括

在ERG蛋白 (ETS相关基因) 中的一种特定的普罗林对白血病的发展至关重要. 针对其与NCoR-HDAC3复合物的相互作用,可能提供新的癌症疗法.

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