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Updated: Jul 16, 2025

Author Spotlight: Developing a Reproducible Method for Isolating Bone Marrow-Derived Macrophages from Neonatal Mice to Advance Early Life Immune Responses
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Author Spotlight: Developing a Reproducible Method for Isolating Bone Marrow-Derived Macrophages from Neonatal Mice to Advance Early Life Immune Responses

Published on: May 24, 2024

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在新生儿单细胞-巨细胞分化过程中干扰Rac1激活会影响M1巨细胞的炎症反应

Hang Fu1,2,3, Ping Zhang4,5, Xiao-Dong Zhao6,7

  • 1Department of Pediatrics, Women and Children's Hospital of Chongqing Medical University, 401147, Chongqing, China. fuhang1987@outlook.com.

Cell death & disease
|September 22, 2023
PubMed
概括

研究人员发现了一种新的方法,通过向新生儿巨细胞中的Rac1来治疗死性肠球炎 (NEC). 抑制Rac1降低了炎症性细胞因子,为早产婴儿提供了一个有前途的治疗途径.

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Quantification of Monocyte Chemotactic Activity In Vivo and Characterization of Blood Monocyte Derived Macrophages

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Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes11:48

Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes

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相关概念视频

Differentiation of Common Myeloid Progenitor Cells01:15

Differentiation of Common Myeloid Progenitor Cells

Common myeloid progenitors (CMPs) are oligopotent cells that can differentiate into granulocytes and macrophages. Granulocytes and macrophages are essential for protecting the body against bacterial, viral, or fungal infections. They migrate from the bone marrow into the circulating blood to reach specific tissue sites where they differentiate and help in immune surveillance. However, they survive only for a few days and must be continuously made available to the organism to maintain a robust...
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