一个改进的传染性模型来检测跨代传播的环境影响
Ingrid David1, Anne Ricard2,3
1GenPhySE, Université de Toulouse, INRAE, ENVT, 31326, Castanet Tolosan, France. ingrid.david@inrae.fr.
Genetics, selection, evolution : GSE
|September 22, 2023
概括
新的环境传染性模型有效地检测和量化跨代环境影响. 该模型改进了现有的方法,因为它考虑了环境对遗传特征的影响,这对野生物种适应至关重要.
科学领域:
- 进化生物学是进化的生物学.
- 定量遗传学 是一种定量遗传学.
- 动物繁殖 动物繁殖
背景情况:
- 非遗传信息 (表观遗传标记,微生物群,文化遗产) 在跨代遗传中发挥作用.
- 这种非遗传遗传是野生物种适应环境变化的关键.
- 现有的传染性模型预测了动物的繁殖潜力,但并没有完全考虑环境影响.
研究的目的:
- 扩展可传染性模型,以纳入对遗传特征的环境影响.
- 引入"与环境共享的可传播性模型",考虑共享的环境共变性.
- 使用概率比测试 (LRT) 测试没有传递的环境影响的零假设.
主要方法:
- 模拟使用两条线动物实验设计进行,其中一条线暴露在特定环境中.
- 评估了"与环境的传染性模型"在检测和量化跨代环境影响方面的表现.
- 将LRT与功率和I型错误率的T测试进行了比较.
主要成果:
- 在检测跨代环境影响方面,LRT表现出高功率 (45-94%),明显优于T测试 (<26%).
- LRT保持了5%的I型错误率,符合预期,而T测试显示了15%的I型错误.
- 增强模型中估计的差异,共变率和路径系数与真实值非常接近.
结论:
- "环境与可传播性模型"是一个强大而有效的工具,用于建模环境影响的垂直传播.
- 这种模型可以更准确地预测世代间受环境因素影响的遗传特征.
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