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Updated: Jul 16, 2025

Generation of High Quality Chromatin Immunoprecipitation DNA Template for High-throughput Sequencing ChIP-seq
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Generation of High Quality Chromatin Immunoprecipitation DNA Template for High-throughput Sequencing ChIP-seq

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在2型糖尿病中推断因果基因GWAS位点通过岛屿细胞中的染色体相互作用

Jason M Torres1, Han Sun2, Vibe Nylander3

  • 1Wellcome Centre for Human Genetics, University of Oxford, Oxford, England, OX3 7BN, UK.

Wellcome open research
|September 22, 2023
PubMed
概括

向染色体构造捕获 (3C) 方法显著提高了识别2型糖尿病致病基因的分辨率和灵敏度. 这种方法增强了对特定遗传位置的基因调节的理解.

关键词:
在Capture-C中使用Capture-C.这些细胞是EndoC-βH1细胞.在GWAS的位置上,GWAS loci染色素相互作用的作用.遗传调节是一种基因调节.人类岛屿小岛.2 型糖尿病 2 型糖尿病

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