在使用基于mRNA的COVID-19疫苗后复发的TIPIC综合征
Georgiana C Sandu1, Gregor Weisser2, Stefan Krämer3
1Department of Neurology and Clinical Neurophysiology, Germany.
Case reports in vascular medicine
|September 22, 2023
概括
在很少情况下,mRNA COVID-19 疫苗可能会导致心血管炎症,原因是心血管动脉短暂周围血管炎症 (TIPIC) 综合征. 这种罕见的副作用在接种疫苗后呈现为部疼痛,需要在差异诊断中考虑.
科学领域:
- 免疫学 免疫学 免疫学
- 神经学 神经学
- 心脏病学 心脏病学
背景情况:
- mRNA COVID-19 疫苗与各种血管并发症有关,包括心肌炎和血栓形成.
- 喉痛 (Carotidynia) 是疫苗接种后较少报告的一种症状.
研究的目的:
- 在mRNA COVID-19疫苗接种后报告心血管炎病例.
- 调查疫苗接种与动脉短暂周围血管炎症 (TIPIC) 综合征之间的潜在联系.
主要方法:
- 一名49岁的妇女在接种斯派克瓦克斯疫苗后出现部疼痛的案例报告.
- 临床评估,诊断成像,以及对其他免疫介导疾病的检查.
- 用普得尼松和阿司匹林治疗.
主要成果:
- 接种疫苗后几天,患者患上左侧心血管炎.
- 图像检测表明,这是一种传动性周脉动炎症 (TIPIC) 综合征.
- 症状通过普得尼松和阿司匹林治疗得到缓解,在病毒感染期间出现轻微复发.
结论:
- 由于TIPIC综合征而导致的二次性心炎可能是mRNA COVID-19疫苗的免疫原副作用.
- 在COVID-19疫苗接种后出现新发部疼痛的患者应考虑TIPIC综合征.
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