在头部和部状细胞癌的初始研究中PET/CT的重要性
Ryan N Hellums1, Priscilla F A Pichardo1, Kenneth W Altman1
1Department of Otolaryngology-Head and Neck Surgery Facial Plastic Surgery Geisinger Medical Center Danville Pennsylvania USA.
OTO open
|September 22, 2023
概括
阳子发射断层扫描/计算机断层扫描 (PET/CT) 显著影响头癌的分期. 这种成像模式确定了近20%的患者的错误分期或错过的第二次原发性恶性瘤.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 核医学就是核医学.
背景情况:
- 头状细胞癌 (HNSCC) 的诊断和分期对于治疗规划至关重要.
- 精确的分期依赖于全面的成像来检测初级瘤,节点参与和远程转移.
- 在初始HNSCC工作中,集成正子发射断层扫描/计算机断层扫描 (PET/CT) 的作用需要进一步阐明.
研究的目的:
- 评估PET/CT对HNSCC.患者在呈现时疾病病期的影响.
- 为了确定临床分期变化的频率和检测PET/CT所导致的第二次原发性恶性瘤.
主要方法:
- 在初始治疗期间接受PET/CT的HNSCC患者的回顾性横截面审查.
- 在PET/CT前后临床分期的比较.
- 对阶段变化或新发现的第二原发性恶性瘤患者的统计分析.
主要成果:
- 在接受PET/CT治疗的238名患者中,11.9% (28) 患者临床上升阶段.
- 在7.6% (18) 的患者中,PET/CT 检测出了第二次原发性恶性瘤.
- 根据PET/CT发现,有7名患者经历了治疗改变.
结论:
- 在HNSCC的精确分期中,PET/CT起着至关重要的作用.
- 排除PET/CT可能会导致不适当的分期或错过的第二次原发性恶性瘤在19.3%的病例中.
- 用PET/CT进行全面的功能成像对于HNSCC的初始预处理工作至关重要.
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